Egypt
Research Article
Cyromazine and Chlorpyrifos Induced Renal Toxicity in Rats: The Ameliorated Effects of Green Tea Extract
Author(s): Tarek M. Heikal, Abdel-Tawab H. Mossa, Gehan I. Kh. Marei and Mona A. Abdel RasoulTarek M. Heikal, Abdel-Tawab H. Mossa, Gehan I. Kh. Marei and Mona A. Abdel Rasoul
In the present study, the protective effect of an aqueous extract of green tea (GT) against renal oxidative damage and nephrotoxicity induced by cyromazine (Cyr), chlorpyrifos (CPF) and their combination in male rats was undertaken. Eight groups containing six rats each were selected. Group I served as control. Groups II, III and IV rats were given a single daily oral doses of Cyr (169.35 mg kg-1, 1/20 LD50, in corn oil), CPF (6.75 mg kg-1 kg-1,1/20 LD50, in corn oil) and their combination for 28 consecutive days, respectively. Group V permitted free access to solubilised GT (1.5%w/v in water) as the sole drinking fluid. Groups VI, VII and VIII rats were given the same doses as groups II, III and IV and simultaneously permitted free access to solubilised GT as the sole drinking fluid. Significant reduction in body weight and elevation in kidney weight were observed in insecticides exp.. Read More»
DOI:
10.4172/2161-0525.1000146
Environmental & Analytical Toxicology received 6818 citations as per Google Scholar report