Australia
Research Article
Safety and Long Term Outcomes with High Flow Nasal Cannula Therapy
in Neonatology: A Large Retrospective Cohort Study
Author(s): Michael McQueen, Jorge Rojas, Shyan C Sun, Robert Tero, Kevin Ives, Frank Bednarek, Larry Owens, Kevin Dysart, George Dungan, Thomas H. Shaffer and Thomas L MillerMichael McQueen, Jorge Rojas, Shyan C Sun, Robert Tero, Kevin Ives, Frank Bednarek, Larry Owens, Kevin Dysart, George Dungan, Thomas H. Shaffer and Thomas L Miller
Objective: High flow nasal cannula therapy (HFT) has been shown to be similar to nasal continuous positive airway pressure (nCPAP) in neonates with respect to avoiding intubation. The objective of the current study is to determine if there are trends for adverse safety and long-term respiratory outcomes in very low birth weight infants (<1500 g) from centers using HFT as their primary mode of non-invasive respiratory support compared to data from the largest neonatal outcomes database (Vermont Oxford Network; VON).
Methods: A multicenter, retrospective analysis of pulmonary outcomes data was performed for the calendar years 2009, 2010 and 2011. Performance of five HFT centers was compared with population outcomes from the VON database. The five HFT centers routinely use flow rates between 4-8 L/min as described by the mechanistic literatu.. Read More»
DOI:
10.4172/2161-105X.1000216
Pulmonary & Respiratory Medicine received 1690 citations as per Google Scholar report