Journal of Cytology & Histology

Ghada N. Mansour

Publications

• Research Article
  Effect of Triclosan on the Renal Cortex of Adult Male Albino Rats and the Possible Protective Role of Ellagic Acid: Histological and Biochemical Study
  Author(s): Zeinab A. Hassan, Manal R. Abd El-Haleem and Ghada N. MansourZeinab A. Hassan, Manal R. Abd El-Haleem and Ghada N. Mansour
  
  Background: Triclosan (TCS) is widely used broad spectrum bactericide. Ellagic acid (EA) has radical scavenging properties. Aim of the work: to assess the structure of the renal cortex after TCS administration and to determine the possible protective role of EA. Materials and Methods: Thirty adult male albino rats were divided into three groups; control group, TCS treated group: TCS was administered 200 mg/kg, once daily for six week, by oral gavages. TCS-EA treated group: received in the same doses of TCS and EA (30 mg/kg) for six weeks. Blood urea nitrogen (BUN), serum creatinine (Sc) and uric acids (UA) were measured. Renal cortex samples were processed for light and electron microscope examination. Results: Examination of TCS treated group revealed increased glomerular cellularity in some c.. Read More»
  DOI: 10.4172/2157-7099.1000285

  Abstract PDF