Journal of Health & Medical Informatics

Gilbert Blaise

Publications

• Research Article
  The Effect of Epidural Morphine-Bupivacaine Combined with a Low Dose of Naloxone on Respiratory Function and Analgesia in Patients with Chronic Low-Back Pain
  Author(s): Alireza Nekoui, Jabril Eldufani, Pierre Mayer and Gilbert BlaiseAlireza Nekoui, Jabril Eldufani, Pierre Mayer and Gilbert Blaise
  
  Context: Hypoventilation and apnea after epidural morphine is a serious concern after surgery and an issue in chronic pain. A low dose of naloxone added to morphine can prevent this complication. Objective: To determine that the low dose of naloxone added to epidural morphine analgesic could change the effect of this opioid in chronic low back pain. In addition, we evaluate its effect on respiratory function and patient satisfaction. Patients: Twenty-seven adults suffering from chronic low back pain (LBP) who were candidates for epidural injection treatment. Intervention: This was a randomized double-blind, uniform crossover, controlled clinical trial. The patients were treated with mixture of morphine-bupivacaine and mixture of morphine-bupivacaine-naloxone. Main outcom.. Read More»
  DOI: 10.4172/2157-7420.1000298

  Abstract PDF