IRCCS Policlinico San Matteo Foundation, Infectious Diseases Department,
Italy
Case Report
Complete Remission of Multicentric Castleman's Disease developed in a HIV+
Patient after the Start of HAART
Author(s): Alessandro Perretti, Valentina Zuccaro, Antonello Malfitano, Giuseppe Barbaro and Giorgio BarbariniAlessandro Perretti, Valentina Zuccaro, Antonello Malfitano, Giuseppe Barbaro and Giorgio Barbarini
In August 2010, we diagnosed a Multicentric Castleman’s Disease (MCD) in a HIV+ patient with generalized lymphadenopathy, splenomegaly and pericardial effusion. A few days before the onset of symptoms, the patient had started anti-retroviral therapy with Abacavir/Lamivudine (ABC/3TC) +Ritonavir-boosted Atazanavir (ATV/r). During the hospitalization he developed a severe pancytopenia with liver failure, and he started immediately the Therapy with steroids, Ganciclovir, and Rituximab. At the 46 months follow-up, the patient is asymptomatic, his biochemical values are essentially normal with a complete regression of the superficial and deep lymphadenopathies... Read More»
DOI:
10.4172/2155-6113.1000337
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