Molecular and Genetic Medicine

Giovanni Cattoli

Publications

• Research Article
  The production and development of H7 Influenza virus pseudotypes for the study of humoral responses against avian viruses
  Author(s): Eleonora Molesti, Giovanni Cattoli, Francesca Ferrara, Eva Böttcher-Friebertshäuser, Calogero Terregino and Nigel TempertonEleonora Molesti, Giovanni Cattoli, Francesca Ferrara, Eva Böttcher-Friebertshäuser, Calogero Terregino and Nigel Temperton
  
  In recent years, high pathogenicity avian influenza (HPAI) virus, H5N1, low pathogenicity avian influenza (LPAI) virus, H9N2, and both HPAI and LPAI H7 viruses have proved devastating for the affected economies reliant on poultry industry, and have posed serious public health concerns. These viruses have repeatedly caused zoonotic disease in humans, raising concerns of a potential influenza pandemic. Despite the focus on the HPAI H5N1 outbreak in 1997 some H7 strains have also shown to be occasionally adaptable to infecting humans. Therefore, applying knowledge of the H5 virus evolution and spread to the development of sensitive serological methods is likely to improve our ability to understand and respond to the emergence of other HPAI and LPAI viruses, present within the avian populations, with the potential to infect humans and other species. In the present study we describe the co.. Read More»
  DOI: 10.4172/1747-0862.1000056

  Abstract PDF