Journal of AIDS & Clinical Research

Giovanni Mazzola

Publications

• Research Article
  Associated Factors and Liver Disease Severity for Decreased Bone Mineral Density in HIV Mono- and HIV/HCV Co-infected Patients
  Author(s): Valentina Li Vecchi, Maurizio Soresi, Lydia Giannitrapani, Giovanni Mazzola, Pietro Colletti, Ilaria Domenica Amico, Fabio Tramuto, Walter Grana, Massimo Midiri, Giuseppe Caruso, Giuseppe Montalto and Paola Di CarloValentina Li Vecchi, Maurizio Soresi, Lydia Giannitrapani, Giovanni Mazzola, Pietro Colletti, Ilaria Domenica Amico, Fabio Tramuto, Walter Grana, Massimo Midiri, Giuseppe Caruso, Giuseppe Montalto and Paola Di Carlo
  
  Objective: We assessed the prevalence and risk factors of decreased bone mineral density (BMD) in patients mono-infected with human immunodeficiency virus (HIV) or co-infected with hepatitis C virus (HIV/HCV). We also evaluated whether bone loss was linked to lipid asset in both groups and to severity of liver fibrosis in the co-infected group. Methods: We consecutively enrolled 194 HIV-patients (129 mono-infected and 65 co-infected). All HIV-patients underwent dual-energy X-ray absorptiometry (DXA), while co-infected patients underwent transient elastography. Advanced liver fibrosis was defined as a median liver stiffness ≥ 9.5 kPa. Fibrosis was also assessed in all the HIVpatients using FIB-4. Results: The overall prevalence of low BMD and osteoporosis was 26.8% and 26.0%, respectively. It was significantly higher among HIV/HCV co-infected tha.. Read More»
  DOI: 10.4172/2155-6113.1000438

  Abstract PDF