Journal of Tissue Science and Engineering

Giulia Silvani

Publications

• Research Article
  Peculiar Characteristics of Human Mesenchymal Stem Cell Clones Suitable as Tissue Engineering Models
  Author(s): Giulia Silvani, Daniela Galli, Laura Benedetti, Gabriele Ceccarelli, Nicola Crosetto, Nicola Crosetto, Carla Olivieri, Cesare Danesino Cesare Danesino and Maria Gabriella Cusella De AngelisGiulia Silvani, Daniela Galli, Laura Benedetti, Gabriele Ceccarelli, Nicola Crosetto, Nicola Crosetto, Carla Olivieri, Cesare Danesino Cesare Danesino and Maria Gabriella Cusella De Angelis
  
  In the last few years? stem cell research contributed to gain a fundamental understanding of how organisms grow and develop and how tissues are maintained throughout adult life. Mesenchymal stem cells (MSC) are self renewing, multipotent cells that are present in many adult tissues, such as bone marrow, adipose tissue, trabecular bone and muscle. More recently they have been found also in skin, liver and other tissues. Dermal skin-derived fibroblasts exhibit mesenchymal surface antigen immunophenotype and differentiation capabilities versus the three main mesenchymal tissues (bone, fat and cartilage). Hereditary Hemorrhagic Telangiectasia affects 1 in 5000 people and leads to abnormal blood vessel formation in skin and mucous membranes. We isolated human dermal fibroblasts from patients with Hereditary Hemorrhagic Telangiectasia (HHT) and healthy controls. In order to.. Read More»
  DOI: 10.4172/2157-7552.1000106

  Abstract PDF