Journal of Clinical Case Reports

Grenier F

Publications

• Case Report
  Child Abuse: A Complex Case Report: Association of Amitriptyline Intoxication and Shaken Baby Syndrome
  Author(s): Grenier F, Paysant F, Durand C, Eysseric H, Bost-Bru C and Scolan VGrenier F, Paysant F, Durand C, Eysseric H, Bost-Bru C and Scolan V
  
  This article concerns the unusual association between two kinds of mistreatment: Shaken baby Syndrome/ Abusive Head Trauma (SBS/AHT) and intentional intoxication by a tricyclic antidepressant (TCA) (amitriptyline). A six-month-old girl was hospitalized in state of coma after several episodes of malaise. The ophthalmologic exams found bilateral retinal and retrohyaloid hemorrhage, the RMI detected non-compressive subdural hematomas localized in the posterior fossa and the brain convexities and the toxicological results were positive for amitriptyline (99.4 μg/L) and its metabolite nortriptyline (154 μg/L) in the blood. All differential diagnoses were eliminated such as glutaric aciduria II, copper metabolism anomaly, and Osteogenesis Imperfecta. The police investigation reports the grand-mother and the father had an amitriptyline prescription. Th.. Read More»
  DOI: 10.4172/2165-7920.1000617

  Abstract PDF