School of Biosciences,
Canterbury, Kent, CT2 7NJ
United Kingdom
Research Article
Morphological and Kinetic Embryological Criteria and Correlation with
Aneuploidy Rates: How Might they Be Used to Choose the Best IVF Embryo
for Transfer?
Author(s): Coates A, Coate B, Holmes L and Griffin DKCoates A, Coate B, Holmes L and Griffin DK
Abstract
Objective: To test the hypothesis that embryos reaching a certain developmental stage at a fixed time point (indicative of growth rate) and those of better morphology are more likely to be euploid than those reaching an earlier stage at the same point and those with poorer morphology. To test the hypothesis that quality of the inner cell mass (ICM) and trophectoderm (TE) independently predict ploidy status. 5 specific age groups were tested
Design: Observational research study, retrospective analysis
Setting: Clinical IVF laboratory, comprehensive chromosome screening (CCS) outsourced to specialist laboratory
Patients: Those undergoing IVF with Comprehensive Chromosome Testing (CCS) by array Comparative Genomic Hybridization (aCGH).
Interventions.. Read More»
DOI:
10.4172/2161-0436.1000129
Human Genetics & Embryology received 309 citations as per Google Scholar report