China
Research Article
No Evidence of HSV Presence in the Serum of Vitiligo Patients
Author(s): Zhe Liu, Rui-Qun Qi, Lian-Shuang Zhao, Xiao-Dong Sun, Da-Yong Dong, Gui-Hua Li, Ya-Ni Lv, Long Geng, Hong-Duo Chen and Xing-Hua GaoZhe Liu, Rui-Qun Qi, Lian-Shuang Zhao, Xiao-Dong Sun, Da-Yong Dong, Gui-Hua Li, Ya-Ni Lv, Long Geng, Hong-Duo Chen and Xing-Hua Gao
Vitiligo is mostly regarded as a consequence of autoimmune response, while the triggering factors remain to be determined. We checked the presence of HSV specific DNA, and IgG and IgM antibodies against HSV, in serum of 90 vitiligo patients by PCR and chemiluminescence methods, respectively. No HSV specific DNA was detected in vitiligo of any types or stages. The seropositivity of antibodies against HSV was similar between the patients and controls. Other approaches should be tried to clarify the role of HSV in the pathogenesis of vitiligo.
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DOI:
10.4172/2376-0427.1000105
Journal of Dermatology and Dermatologic Diseases received 4 citations as per Google Scholar report