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Journal of Bioanalysis & Biomedicine

ISSN: 1948-593X

Open Access

Günter Müller

Ludwig-Maximilians-University Munich,
Biocenter, Department Biology, Genetics, 82152 Martinsried near Munich
Germany

Publications
  • Research Article
    Novel Tools for the Study of Cell Type-Specific Exosomes and Microvesicles
    Author(s): Günter MüllerGünter Müller

    Many cell types release exosomes and microvesicles (EMVs) with a size range from 0.05-5 μm, harbouring receptors, bioactive and signaling proteins, molecular mediators and nucleic acids for cell-to-cell communication. Microvesicles bud directly from the plasma membrane, in contrast to exosomes which are derived from multivesicular bodies within the cell. Increased levels of EMVs have been observed in plasma, urine and other body fluids in patients suffering from a wide range of common complex diseases, including vascular, metabolic, lung, autoimmune and neurodegenerative diseases, chronic inflammation and cancer. EMVs may affect target cells directly by surface-bound ligands, transferred surface receptors and membrane-associated enzymes, such as glycosylphosphatidylinositolanchored proteins, or delivered cytoplasmic or membrane-associated constituents, such as cytosolic proteins, m.. Read More»
    DOI: 10.4172/1948-593X.1000063

    Abstract PDF

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Citations: 3099

Journal of Bioanalysis & Biomedicine received 3099 citations as per Google Scholar report

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