Journal of Biometrics & Biostatistics

H Timothy Bunnell

Publications

• Research Article
  Piecewise Mixed Effects Model to Compare the Weight-gain Patter ns Before and After Diagnosis of Asthma in Children Younger than 5 Years
  Author(s): Md Jobayer Hossain, Li Xie, Jason E Lang, Timothy T Wysocki, Thomas H Shaffer and H Timothy BunnellMd Jobayer Hossain, Li Xie, Jason E Lang, Timothy T Wysocki, Thomas H Shaffer and H Timothy Bunnell
  
  Asthma and obesity are two significant public health problems that both originate in early childhood and have shared risk factors and manifestations. Studies suggest a strong association between asthma development and subsequent accelerated weight gain. Children are diagnosed with asthma in early childhood and are often exposed to factors associated with rapid weight gain. This article intends to demonstrate an innovative application of the piecewise mixed effects model to characterize the difference in the temporal rate of change in BMIz, the standardized scores of body mass index and weight-for-length that measure weight status, before and after asthma diagnosis in children younger than 5 years. The data consist of unique sequences from 1194 children's clinic visits during the first 5 years of life. We used a knot at the time of diagnosis and detected a differential weight-gain patt.. Read More»
  DOI: 10.4172/2155-6180.1000248

  Abstract PDF