Medicinal Chemistry

Haci Bayram Zengin

Publications

• Research Article
  Amoebicidal Effect of Poly (Maleic Anhydride-Co-Vinyl Acetate) Copolymer on Entamoeba Histolytica Trophozoites
  
  Author(s): Gulderen Karakus, Ali Fazil Yenidunya, Haci Bayram Zengin, Erdogan Malatyali and Semra ÖzçelikGulderen Karakus, Ali Fazil Yenidunya, Haci Bayram Zengin, Erdogan Malatyali and Semra Özçelik
  
  Poly (maleic anhydride-co-vinyl acetate) (MAVA) copolymer was synthesized by free-radical copolymerization in methyl ethyl ketone (MEK) at 80ºC, using benzoyl peroxide (BPO) as the initiator. The radical chain copolymerization was confirmed by Fourier Transform Infrared (FTIR) and Nuclear Magnetic Resonance (1H-NMR) spectra. Copolymer surface morphology was visualized by scanning electron microscopy (SEM). After these characterization studies, the amoebicidal effect of MAVA was investigated on E.histolytica trophozoites using differing copolymer concentrations and periods of time. Results indicated that MAVA killed all the trophozoites at 32 mg/mL concentration in 3 h. .. Read More»
  DOI: 10.4172/2161-0444.1000103

  Abstract