Indiana
Research Article
Short-Term Exposure to Haze Air Pollution Induces Acute Airway Inflammation and Lung Function Reduction in Healthy Adult Subjects
Author(s): Haibin Li, Yanqin Liu, Sanqiao Yao, Yuefei Jin, Yixin Luo, Wenyang Li, Chengyu Song, Chonglun Liu, Ziye Wang and Weidong WuHaibin Li, Yanqin Liu, Sanqiao Yao, Yuefei Jin, Yixin Luo, Wenyang Li, Chengyu Song, Chonglun Liu, Ziye Wang and Weidong Wu
Haze air pollution with high levels of PM has frequently took place in many areas of China in the past few years. However, the health effect of shirt-term exposure to haze air pollution has not been thoroughly characterized. This study aimed to determine the acute effect of haze exposure on respiratory system of healthy adult subjects, specifically on airways and lung function. Thirty healthy adult subjects were recruited and airway inflammation and lung function alterations examined under control and haze air pollution (157.33 μg/m for mean concentration of PM ) conditions, respectively. Airway inflammation was assessed by sputum induction while lung function was measured using spirometry. It was shown that 24-h exposure to haze air pollution could increase the levels of inflammatory mediators including interleukin-6 (IL-6), IL-8, and tumor necrotic factor-α (TNF-α), a.. Read More»
DOI:
10.4172/2161-0525.1000555
Environmental & Analytical Toxicology received 6818 citations as per Google Scholar report