Journal of Computer Science & Systems Biology

Hans Lehrach

Publications

• Review Article
  Functional Dynamics: From Biological Complexity to Translation and Impact in Healthcare Systems
  Author(s): Jonathan A. Lal, Ralf Sudbrak, Hans Lehrach and Angela BrandJonathan A. Lal, Ralf Sudbrak, Hans Lehrach and Angela Brand
  
  Biological complexity at a molecular and physiological level is dynamically translucent and requires a systemwide computational approach to possibly elucidate underlying mechanisms for medical and public health applications. Functional dynamics is ideal to study molecular functions given biological functions are dependent on the dynamic nature of networks it operates within. However, environmental factors significantly affect the molecular dynamics in biology, which still needs to be incorporated in study of functions for medical applicability. Through technological innovation medicine is seeing a potential shift in demand for personalized interventions, which has not been fully realized yet. Also the applicability of functional dynamics’ utility seems not visible in healthcare systems. This article addresses the above mentioned issues, challenges in.. Read More»
  DOI: 10.4172/jcsb.1000104

  Abstract PDF