Journal of Clinical Case Reports

Hela Hariz

Publications

• Case Report
  Rosai-Dorfman Disease in a 23-Year-Old Patient
  Author(s): Hela Hariz, Sameh Marzouk, Raida Ben Salah, Noura Saidi, Moez Jallouli, Tahia Boudawara and Zouhir BahloulHela Hariz, Sameh Marzouk, Raida Ben Salah, Noura Saidi, Moez Jallouli, Tahia Boudawara and Zouhir Bahloul
  
  Rosai-Dorfman Disease (RDD) also known as Sinus Histiocytosis With Massive Lymphadenopathy (SHML) is a rare and benign non- Langerhans histiocytosis. First described in 1965 by Destombes [1] then in 1969 by Rosai and Dorfman, this disease is characterized by benign histiocytic proliferation with frequent lymphophagocytosis (emperipolesis) [2]. All ages are affected but most of the patients present before age 20, with a slight male predominance [3]. Rosai-Dorfman disease usually presents as bilateral, massive and painless cervical lymphadenopathy [2]. Extra-nodal involvement is found in 30-40% of cases and is more common in the head and neck region [3]. The disease is often benign and self limiting requiring only observation. In some cases, the condition can be severe. Several treatments have been used with varying efficiency [4]. We report a case of RDD in a male Tunisian patient trea.. Read More»
  DOI: 10.4172/2165-7920.1000291

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