Journal of Clinical Case Reports

Helder Picarelli

Publications

• Case Report
  Complete Response to Radiotherapy in a Pineal Parenchymal Tumor of Intermediate Differentiation
  Author(s): Helder Picarelli, Joao Victor Savajoli, Olavo Feher and Manoel Jacobsen TeixeiraHelder Picarelli, Joao Victor Savajoli, Olavo Feher and Manoel Jacobsen Teixeira
  
  Background and Importance: Approximately 20 percent of parenchymal pineal tumors (PPT) arise from the epithelial cells and are extremely rare, especially in adults, accounting for less than 1 percent of all primary brain tumors in Europe and North America. PPT of intermediate differentiation (PPTID) was recognized as a new entity and introduced in the 2007 WHO classification, corresponding to grades II (GII) or III (GIII). Previous studies had suggested its potentially aggressive behavior and tendency for cerebrospinal fluid seeding. A standard treatment for these tumors has not yet been defined. The gross total surgical resection is indicated whenever technically feasible and the impact of adjuvant radiotherapy and chemotherapy is not established. In fact, little is known about the radiation and chemotherapy sensitivity of these tumors. Clinical Presentation: We describe a case of a .. Read More»
  DOI: 10.4172/2165-7920.1000725

  Abstract PDF