Journal of Clinical Case Reports

Hichem Khenioui

Publications

• Case Report
  Intra Detrusor Botulinum Toxin and Lower Limbs Motor Deficit: About 2 Clinical Cases
  Author(s): Hichem Khenioui, Morgane Le berre, Caroline Massot, Anne Blanchard, Christian Marcelli and Cecile DonzeHichem Khenioui, Morgane Le berre, Caroline Massot, Anne Blanchard, Christian Marcelli and Cecile Donze
  
  Objective: To demonstrate how a single intra detrusor botulinum toxin injection could be responsible for lower limbs proximal motor deficit. Results: Two women-37 and 38 years old-presenting with secondary progressive multiple sclerosis, having received intra detrusor botulinum toxin injections (400 BOTOX® U and 750 DYSPORT® U) due to major neurogenic detrusor over activity with high-pressure and risks of uro-nephrologic complications despite an efficient-dose anticholinergic bi-therapy (DITROPAN®/CERIS®). Few days in post-injection they present heavy tiredness, instability of the pelvis, and a major reduction of the walking distance. Those symptoms last for several months. During the emergency neurology consultation set up in the event of a new relapse, an aggravation of the paraparesis at the proximal level is observed. This deficit accounts for the .. Read More»
  DOI: 10.4172/2165-7920.1000761

  Abstract PDF