Japan
Research Article
Azilsartan is More Effective as Compared to Olmesartan in Hemodialysis Patients with Uncontrolled Hypertension
Author(s): Akira Ukimura, Hirohisa Matsuda, Yoko Yamauchi, Kazuhisa Yamamoto, Kei Hirai, Nobuyuki Ueno, Hideaki Yasuda and Shuta OnoAkira Ukimura, Hirohisa Matsuda, Yoko Yamauchi, Kazuhisa Yamamoto, Kei Hirai, Nobuyuki Ueno, Hideaki Yasuda and Shuta Ono
Background: Azilsartan is a new angiotensin receptor blocker with more continuous antihypertensive effects. The objective of this study was to demonstrate the efficacy and safety of azilsartan in hemodialysis patients with uncontrolled hypertension.
Methods: Twenty-two hemodialysis patients treated with multiple antihypertensive drugs including olmesartan (20- 40 mg/day) were enrolled in this retrospective observational study. Blood pressure was measured in the morning and evening for a week at baseline and after switching from olmesartan to azilsartan. The patients’ mean blood pressure at baseline was 171/71 mmHg. Olmesartan (20-40 mg/day) was switched to azilsartan with the same dose. An electrocardiogram, an echocardiogram, and measurement of the ankle-brachial index were performed in all patients, and the echocardiogram showed left ventricular hypertrophy in all pati.. Read More»
DOI:
10.4172/2161-0959.1000193
Journal of Nephrology & Therapeutics received 784 citations as per Google Scholar report