Journal of Clinical Case Reports

Hironori Koga

Publications

• Case Report
  Successful Down-staging of Hepatocellular Carcinoma with Intra-arterial Therapy Prior to Liver Transplantation: A Case Report
  Author(s): Hideki Iwamoto, Hiroaki Nagamatsu, Takashi Niizeki, Shigeo Shimose, Tomotake Shirono, Hironori Koga, Akinobu Taketomi, Ryoko Kuromatsu and Takuji TorimuraHideki Iwamoto, Hiroaki Nagamatsu, Takashi Niizeki, Shigeo Shimose, Tomotake Shirono, Hironori Koga, Akinobu Taketomi, Ryoko Kuromatsu and Takuji Torimura
  
  Background: Down-staging strategy of Hepatocellular carcinoma (HCC) prior to Liver Transplantation (LT) is important for preventing drop-out from the waiting list for LT or further enlargement of the adaptation of LT. Hepatic arterial infusion chemotherapy with cisplatin in lipiodol and 5-fluorouracil (HAIC with lipiodol) is a novel and effective treatment for advanced HCC. Here we report a successful down-staging case of HCC by a series of therapeutic strategies using HAIC with lipiodol that provided an effective bridge to LT. Case Report: We report a 48-year-old patient with severe liver cirrhosis, a 7.5 cm primary HCC in segment 8 and a 1.2 cm satellite lesion in segment 4, which was outside both Milan Criteria and University of California, San Francisco (UCSF) Criteria. We offered HAIC with lipiodol therapy using a temporary indwelling catheter system with intent to down-stage pri.. Read More»
  DOI: 10.4172/2165-7920.1000655

  Abstract PDF