Journal of Nephrology & Therapeutics

Hiroyo Sasaki

Publications

• Case Report
  Isolated Renal Sarcoidosis Presenting with Granulomatous Interstitial Nephritis: A Case Report and Review of the Literature
  Author(s): Yoichiro Chikamatsu, Izaya Nakaya, Mayumi Yahata, Hiroyo Sasaki, Kazuhiro Yoshikawa, Tsutomu Sakuma and Jun SomaYoichiro Chikamatsu, Izaya Nakaya, Mayumi Yahata, Hiroyo Sasaki, Kazuhiro Yoshikawa, Tsutomu Sakuma and Jun Soma
  
  Background: Sarcoidosis is a multi-system disorder characterized by noncaseating epitheloid granuloma in multiple organs. However, granulomatous interstitial nephritis in the absence of extrarenal renal lesions is very rare. Case presentation: A 64-year-old male presented with a weight loss of 10 kg and an increase in serum creatinine from 1.1 to 4.8 mg/dl over a 1-year period. At admission, no proteinuria or hematuria was found, although serum creatinine was 5.1 mg/dl and was associated with slight increases in serum angiotensin converting enzyme and calcium levels. Renal biopsy revealed granulomatous interstitial nephritis with noncaseating epitheloid cells. The patient was diagnosed with sarcoidosis, although no extrarenal sarcoid lesion was found. Oral prednisolone was effective, with normalization of serum creatinine levels 2 weeks later. A review of the literature showed that is.. Read More»
  DOI: 10.4172/2161-0959.S1-008

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