Journal of Clinical Case Reports

Hong Kean Ooi

Publications

• Case Report
  T-Cell Prolymphocytic Leukemia Accompanied by Plural M-Proteins with Myelodysplastic Syndrome in a Nonagenarian
  Author(s): Nagahito Saito, Katsuhiro Higashiura, Kenta Honma, Shinji Kurosawa, Kazunori Ehata, Tomoyuki Yanami, Katsumi Katagiri, Hiroyuki Sugiki and Hong Kean OoiNagahito Saito, Katsuhiro Higashiura, Kenta Honma, Shinji Kurosawa, Kazunori Ehata, Tomoyuki Yanami, Katsumi Katagiri, Hiroyuki Sugiki and Hong Kean Ooi
  
  T-cell Pro-Lymphocytic Leukemia (T-PLL) is a rare disease caused by malignancy of mature post-thymic T-cell. Myelodysplastic Syndrome (MDS) is caused by abnormal differentiation of myeloid lineage cells resulting in myeloid leukemia. Both of these hematological disorders are frequently diagnosed in elderly persons. Myeloid lineage is believed to be situated at the position far from lymphoid one as it is regarded on a tree diagram about the blood cell maturation. We reported herein a rare case of T-PLL accompanied by plural M-proteins with MDS a nonagenarian. The 96 years old patient was admitted to our hospital because of lymphocytosis and abnormal lymphocytes. From the bone marrow aspirate, biopsy and hematological findings, abnormalities were observed in cells of three different lineages, namely, (i) neutrophils with hypersegmented-nuclei (ii) erythroblasts with nuclear division, la.. Read More»
  DOI: 10.4172/2165-7920.1000131

  Abstract PDF