Peking Union Medical College and Chinese Academy of Medical Sciences,
Beijing
China
Research Article
Increased Circulating Apoptotic CD31+/CD42b- and Activated CD62E+ Endothelial Micro Particles in Coronary Artery Disease
Author(s): Shuai-Shuai Hu, Hong-Gang Zhang, Qiu-Ju Zhang and Rui-Juan XiuShuai-Shuai Hu, Hong-Gang Zhang, Qiu-Ju Zhang and Rui-Juan Xiu
Objective: To examine the phenotypes of endothelial microparticles and platelet microparticles in order to identify a sensitive endothelial microparticle biomarker for monitoring endothelial dysfunction in patients with coronary artery disease, and to examine the mechanisms underlying endothelial dysfunction.
Methods: Thirty-three coronary artery disease patients and 53 healthy subjects were recruited. The absolute numbers of endothelial microparticles and platelet microparticles were measured by flow cytometry, and the clinical characteristics of patients and healthy subjects were recorded. Spearman’s correlation analysis and multiple linear regression analysis were performed to analyse the correlation between endothelial microparticles and platelet microparticles, and between microparticles and clinical data.
Result.. Read More»
DOI:
10.4172/2167-1095.1000167
Journal of Hypertension: Open Access received 614 citations as per Google Scholar report