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Review Article
Sequential Combination of Serum Pyruvate Kinase Isoenzyme M2 and Colonoscopy-A Promising Screening Protocol for Colorectal Cancer Early Diagnosis
Author(s): Hong-Hong Zhu and Shu ZhengHong-Hong Zhu and Shu Zheng
Background: Early diagnosis and treatment through mass screening is practical against colorectal cancer (CRC). Low compliance for current screening tests affects the effectiveness of CRC mass screening. An efficient screening protocol with high compliance is needed for CRC mass screening. Methods: Systematic searches were done through Medline and Cochrane Library databases - initial Medline searches were in February 2010 and additional searches in March/April 2010. Search terms included [(“Colorectal cancer” AND “screening program” AND “incidence”) OR (“Colorectal cancer” AND “screening program” AND “mortality”)] AND [“fecal occult blood test” OR “sigmoidoscopy” OR “colonoscopy” OR “Double-contrast barium enema”]. Results: This review explored the current.. Read More»
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