Molecular Biomarkers & Diagnosis

Hongxia Dan

Publications

• Opinion Article
  Impaired Pattern of Endothelial Cell-Derived Microparticles in Heart Failure Patients with Preserved and Reduced Left Ventricular Ejection Fraction
  Author(s): Huamei Yang, Min Qiu, Yu Zhou, Lu Jiang, Hongxia Dan and Qianming ChenHuamei Yang, Min Qiu, Yu Zhou, Lu Jiang, Hongxia Dan and Qianming Chen
  
  The prevalence of heart failure with preserved left ventricular ejection fraction (HFpEF) rises consequently within past decades. Both phenotypes of HF, i.e. HFpEF and HF with reduced EF (HFrEF), have exhibited similar cardiovascular mortality rates and admission rates, while development and progression of HFpEF and HFrEF associate with different co-morbidities. Understanding of the pathophysiological mechanisms of the two phenotypes of HF is essential for discovery of future new treatments. Biomarkers reflecting several stages of failing heart evolution and different pathophysiological faces of HF (N-terminal pro brain natriuretic peptide, high-sensitivity troponin T, and galectin-3) have been implemented into routine clinical practice to increase diagnostic and predictive capabilities of clinical-based stratification models. Recent clinical studies have .. Read More»
  DOI: 10.4172/2155-9929.1000288

  Abstract PDF