Journal of Biometrics & Biostatistics

Hua Liang

Publications

• Research Article
  Model Tumor Pattern and Compare Treatment Effects Using Semiparametric Linear Mixed-Effects Models
  Author(s): Changming Xia, Jianrong Wu and Hua LiangChangming Xia, Jianrong Wu and Hua Liang
  
  To analyze responses of solid tumor to treatments and to compare treatment effects with antitumor therapies, we applied semiparametric mixed-effects models to fit tumor volumes measured over a period. The population and individual nonparametric functions were approximated by smoothing spline. We also proposed an intuitive method for a comparison of the antitumor effects of two different treatments. Biological interpretation was also discussed... Read More»
  DOI: 10.4172/2155-6180.1000168

  Abstract PDF