College of Stomatology,
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China
Review Article
Effect of FGF/FGFR Signal in Fluid Shear Stress and Estrogen Regulating Bone Metabolism
Author(s): Xia-Yan Luo, Yun Yang and Hui-Qiang SunXia-Yan Luo, Yun Yang and Hui-Qiang Sun
Estrogen and fluid shear stress (FSS) play an important role in bone metabolism, displaying a synergistic effect. Fibroblast growth factors (FGFs) are also of great importance in bone development before and after birth. FGFs regulate downstream signaling pathway by activating FGF receptors (FGFRs) to control the expression of bone tissue cells. This paper conducts a brief discussion of the effect of FGF/FGFR as well as fluid shear stress and estrogen in bone metabolism regulation... Read More»
DOI:
10.4172/2168-9547.1000205
Molecular Biology: Open Access received 607 citations as per Google Scholar report
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