Saudi Arabia
Research Article
Protective Effect of Zinc (Zn) on the Histology and Histochemistry of Liver and Kidney of Albino Rat Treated with Cadmium
Author(s): Alsayed Ali Mahran, Husam Eldien H. Osman, Ahmed M. A. Abd El-Mawla and Adel M. AttiaAlsayed Ali Mahran, Husam Eldien H. Osman, Ahmed M. A. Abd El-Mawla and Adel M. Attia
The protective effect of zinc (Zn) on the liver and kidney of albino rats exposed to intraperitoneal injection of cadmium chloride (CdCl2) was studied. Light microscopic examination for rats which were injected intraperitonealy with of 0.16 mg CdCl2/kg of body weight for 8 weeks indicated severe histological changes in both liver and kidney. In liver, a blurred trabecular structure, vacuolar degeneration and increased density of nuclear chromatin with very compact nuclear structure were found in hepatocytes. Moreover; mononuclear cell infiltrations and necrosis of single cells were also observed. In the kidney tubules, degeneration and hypertrophy of epithelial cells and dilation in the glomeruli were also observed. The effects of cadmium on the ultrastructures of both organs were studied. There are ultrastructural damages appeared in both organs as nuclear membrane damage, chromatin .. Read More»
DOI:
10.4172/2157-7099.1000123
Journal of Cytology & Histology received 2476 citations as per Google Scholar report