Molecular Biomarkers & Diagnosis

Ibtissem Messal

Publications

• Research Article
  Study of Association Between the Polymorphism of MICA Gene (met 129 val) and Ankylosing Spondylitis in a Sample of the Population of Western Algeria
  Author(s): Noria Bouras, Ahmed Benzaoui, Ibtissem Messal, Nadjet Boushaba and Abdallah BoudjemaNoria Bouras, Ahmed Benzaoui, Ibtissem Messal, Nadjet Boushaba and Abdallah Boudjema
  
  Ankylosing spondylitis (AS) is a chronic inflammatory rheumatism characterized by a predominantly axial (spinal) localization, followed by joint damage and enthesis. The AS may be associated with other conditions such as reactive arthritis, psoriatic arthritis, chronic inflammation of the intestine and pulmonary manifestation. In this case, we speak of Spondylarthroparies (SPA). The etiology of AS is not well known, however, genetic factors as well as environmental factors can play a very important role in the onset of the disease. Although several genes appear to be associated with SA, the concept of genetic ground relies heavily on the association with HLA-B27 specificity. Recently, the MICA gene has aroused the interest of several studies of associations MICA and autoimmune diseases (MAI), in particular, the association MICA and SA. In our work, we are interested in the polymorphis.. Read More»
  DOI: 10.4172/2155-9929.1000345

  Abstract PDF