Faculty of Science, Department of Biology, Vezneciler, 34459, Istanbul
Turkey
Research Article
A Verification of Treatment Protocol in Fractionated Radiotherapy by Biological Dosimetry
Author(s): Idil ÖNER, Tuncay ORTA, Melek Özlem KOLUSAYIN, Süreyya GÜNEBAKAN, Asuman Kaynar Öztaş and Mustafa ÜnsalIdil ÖNER, Tuncay ORTA, Melek Özlem KOLUSAYIN, Süreyya GÜNEBAKAN, Asuman Kaynar Öztaş and Mustafa Ünsal
In radiation therapy of cancer, any possible mistakes that may occur in prescribed tumour dose calculation and/ or in treatment set up could also be checked by the biological dosimetry. In order to verify this, 20 patients having pelvic area tumours with no prescribed chemotherapy were selected. Their peripheral blood samples were collected before starting fractionated radiotherapy and at some definite time during treatment. Equivalent whole body doses (EWBD) were calculated from patient’s weights, irradiated volumes and total tumor doses given until the date of blood sample collection during treatment. Each patient’s EWBD was given in vitro to blood samples that were collected before starting radiotherapy. Radiation induced chromosome damage in lymphocytes were measured by micronucleus (MN) induction.
The relationship between the micronucleus frequencie.. Read More»
DOI:
10.4172/2155-9619.1000116
Nuclear Medicine & Radiation Therapy received 706 citations as per Google Scholar report