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Case Report
Intravascular Large B-Cell Lymphoma Mimicking Central Nervous System Vasculitis
Author(s): Fischer M, Stockhammer G, Pfausler B and Iglseder SFischer M, Stockhammer G, Pfausler B and Iglseder S
Intravascular large B-cell lymphoma (IVBCL) represents a rare subtype of extranodal diffuse large B-cell lymphoma characterized by selective growth of neoplastic cells within the lumen of small and medium-sized vessels. The clinical spectrum is heterogeneous dominated by neurological and skin manifestations. Intra-vitam diagnosis still remains challenging and usually requires brain biopsy since no pathognomonic neuroradiological findings do exist for IVBCL. We report on the case of a 65-year old male patient presenting with multifocal neurological signs and symptoms including cognitive deficits, aphasia and paraparesis as leading features. Imaging findings were suggestive for cerebral vasculitis prompting initiation of steroid treatment. After initial stabilization the patient deteriorated in spite of systemic steroid treatment, developed severe sepsis and.. Read More»
DOI:
10.4172/2165-7920.1000767
Journal of Clinical Case Reports received 1295 citations as per Google Scholar report