Medicinal Chemistry

Ince N

Publications

• Research Article
  The Analytical Performances of Four Different Glycated Hemoglobin Methods
  Author(s): Genc S, Gurdol F, Kanmaz-Ozer M, Ince N, Ozcelik F and Omer BGenc S, Gurdol F, Kanmaz-Ozer M, Ince N, Ozcelik F and Omer B
  
  Objectives: The analytical performances of the Sebia capillary electrophoresis (CE), Roche turbidimetric inhibition immunoassay (TINIA), Tosoh G8 cation-exchange high-performance liquid chromatography (HPLC) and Premier boronate affinity chromatography methods were evaluated. Capillary electrophoresis (CE) was accepted as a comparative method. Design and Methods: This study comprised randomly chosen 224 whole blood samples from the diabetic and non-diabetic patients. HbA1c level was quantified using four methods as follows: Roche TINIA, Premier Hb9210 boronate affinity chromatography, Tosoh G8 cation-exchange HPLC and Sebia CE. The analytical performances of the methods were evaluated with imprecion, bias estimation and comparison studies. Results: The results of all pre.. Read More»
  DOI: 10.4172/2161-0444.1000185

  Abstract PDF