Journal of AIDS & Clinical Research

Indranil Thakur

Publications

• Research Article
  A Comparative Insight into the Incidence of Steven Johnson Syndrome/ Toxic Epidermal Necrolyis among the Immunocompromized Patient Populace of Eastern India with a Distinctive Emphasis on the Possible Association of Human Cytomegalovirus
  Author(s): Aroni Chatterjee, Indranil Thakur, Sabbir Ansari, Rajendra Prasad Chatterjee, Rathindranath Sarkar, Shuvashish Kamal Guha and Nilanjan ChakrabortyAroni Chatterjee, Indranil Thakur, Sabbir Ansari, Rajendra Prasad Chatterjee, Rathindranath Sarkar, Shuvashish Kamal Guha and Nilanjan Chakraborty
  
  Stevens-Johnson syndrome (SJS) and its more advanced form, Toxic Epidermal Necrolysis (TEN) are severe adverse cutaneous reactions that predominantly involve skin and mucous membranes. In view of the current dearth of documented knowledge, this study the first of its kind from India was designed to categorically distinguish and compare the different associated factors and clinical manifestations relevant to the development of SJS/TEN syndrome among the immunocompromised (Human Immunodeficiency Virus 1 seropositive) patients in Eastern India. 16 out of 29 patients (55.1%) were found to be suffering from drug induced SJS or TEN, while the rest (44.8%) had severe pathogenic involvements. Neviraprine use was found to be the major cause among drug involved SJS (53.8%) and TEN (66.66%) cases followed by allopurinol use. The frequency of incidence of kidney disease (67% in SJS and 54% in TEN.. Read More»
  DOI: 10.4172/2155-6113.1000706

  Abstract PDF