Nuclear Medicine & Radiation Therapy

Ismail Essadi

Publications

• Research Article
  Combination of Trastuzumab and Radiotherapy in the Adjuvant Treatment of Breast Cancer: A Single Center Experience and Focus on the Cardiac Safety
  Author(s): Ismail Essadi, Issam Lalya, Abdelhamid Elomrani, Mouna Khouchani and Rhizlane BelbarakaIsmail Essadi, Issam Lalya, Abdelhamid Elomrani, Mouna Khouchani and Rhizlane Belbaraka
  
  Background: The main toxicity of trastuzumab, is the alteration of cardiac function. The objective of this study is to examine the acute cardiotoxicity of the combination of Radiotherapy (RT) and trastuzumab in the adjuvant treatment of breast cancer. Materials and Methods: This is a retrospective study of 41 patients followed for localized breast cancer, treated by multimodal strategy combining chemotherapy, Radiotherapy and trastuzumab as adjuvant treatment in the medical oncology department at the Ibn Sina Military hospital of Marrakesh. Results: All patients underwent adjuvant RT on the wall, including 17 on the left side. The median value of the Left Ventricular Ejection Fraction (LVEF) before starting treatment was 64%. The median value of the absolute decrease of LVEF, after the end of RT, was of the order o.. Read More»
  DOI: 10.4172/2155-9619.1000355

  Abstract PDF