Nuclear Medicine & Radiation Therapy

Issam Lalya

Publications

• Case Report
  Intracranial Germinoma: Successful Management by Chemotherapy and Intensity Modulated Radiation Therapy
  Author(s): Issam Lalya, Abdelhak Maghous, El Amin Marnouche, Noha Zaghba, Khalid Andaloussi, Mohamed Elmarjany, Khalid Hadadi, Hassan Sifat, Ismail Essadi and Hamid MansouriIssam Lalya, Abdelhak Maghous, El Amin Marnouche, Noha Zaghba, Khalid Andaloussi, Mohamed Elmarjany, Khalid Hadadi, Hassan Sifat, Ismail Essadi and Hamid Mansouri
  
  Introduction: Germinomas are malignant intracranial germ cell tumors, usually found in pineal region. These tumors are exquisitely sensitive to radiation. Whole ventricle radiation (RT) with a boost field to the primary tumor is the standard treatment for localized germinomas. RapidArc radiotherapy is considered an excellent technological advance that shows great potential for producing highly conformal doses to treatment volumes. Case report: We present a case of intracranial germinoma who achieved a partial remission after four courses of chemotherapy induction. The patient received whole ventricular radiation therapy followed by a boost to the tumor and its margin to a total dose of 40 Gy using RapidArc radiotherapy over the course of 5 weeks. Any toxicity has been noted during the treatment. Early post treatment imaging showed a complete re.. Read More»
  DOI: 10.4172/2155-9619.1000341

  Abstract PDF