Journal of Nephrology & Therapeutics

J Tomazic

Publications

• Research Article
  Cytomegalovirus Infection Associated Neutropenia and Acute Kidney Graft Rejection
  Author(s): Z Veceric-Haler, D Kovac, J Tomazic and J LindicZ Veceric-Haler, D Kovac, J Tomazic and J Lindic
  
  Background: Cytomegalovirus (CMV) infection, neutropenia occurrence and mycophenolate (MMF) dose reduction are associated with an increased risk of acute kidney graft rejection. The aim of our retrospective clinical study was to evaluate the association of CMV associated neutropenia with a consequent MMF dose reduction and acute kidney graft rejection. Method: 161 patients transplanted from January 2005 till December 2010, who received anti-CD25 antibodies induction, MMF, calcineurin inhibitor and steroids, were retrospectively analyzed for the incidence of neutropenia (leucocyte count <4.0 x 106/mL with reduced rate of neutrophils to <1.6 x 106/mL in differential white blood cell count, CMV viremia (>150 virus copies/mL detected by polymerase chain reaction), MMF dose modification, granulocyte colony-stimulating factor (G-CSF) therapy and rejection episodes. Results: Neutr.. Read More»
  DOI: 10.4172/2161-0959.1000293

  Abstract PDF