Journal of Nephrology & Therapeutics

Jagabandhu Ghosh

Publications

• Review Article
  Hemolytic Uremic Syndrome
  Author(s): Jagabandhu Ghosh, Dipankar Gupta and Nibedita ChattopadhyayJagabandhu Ghosh, Dipankar Gupta and Nibedita Chattopadhyay
  
  Hemolytic uremic syndrome (HUS), a common cause of acute renal failure (ARF) in children, consists of triad of microangiopathic haemolytic anemia (MAHA), thrombocytopenia, and ARF. The aim of the present article is to have a recent overview of HUS including its incidence, etiopathogenesis, clinical profile and management. It consists of two types a) Diarrhoea associated i.e. classical also called D+ HUS b) Non-diarrhoea associated i.e. atypical also called D- HUS. D+ HUS is caused mostly by Escherichia coli or occasionally by Shigella dysenteriae. The causes of HUS are infections, genetic defects, systemic diseases and drugs. The atypical form commonly presents with recurrent or chronic persistent attack. Thrombotic microangiopathy (TMA), the pathologic hallmark, includes HUS, atypical HUS (aHUS), thrombotic thrombocytopenic purpura (TTP) which is characte.. Read More»
  DOI: 10.4172/2161-0959.1000239

  Abstract PDF