Journal of Bioprocessing & Biotechniques

Jakub Jaroszewicz

Publications

• Research Article
  Architecture and Properties of PUR/Calcite Composite Scaffolds for Bone Tissue Engineering
  Author(s): Ida Dulinska-Molak, Jakub Jaroszewicz and Krzysztof J KurzydlowskiIda Dulinska-Molak, Jakub Jaroszewicz and Krzysztof J Kurzydlowski
  
  Bone tissue has a composite nature given by a highly complex and well-harmonized structure of organic and inorganic components on the microscale, macroscale and nanoscale. Thus, biodegradable composite scaffolds made of poly (ε-caprolactone) urethane (PCL_PUR) porous matrix and calcium carbonate (CaCO3) were developed and studied for bone tissue engineering. The aim of this work was to examine the structure of new polyurethane/calcite composites. Micro-computer tomography (μ-CT) and image analysis enabled 3D visualization and quantification of the porosity, wall thickness and internal pore size distribution. The fabricated porous polyurethane composites exhibited porosity >70% with a pore size not exceeding 450 μm and wall thickness about of 50 μm in size. The mechanical properties of the foams were evaluated using Dynamic Mechanical Analysis (DMA). In-vitro bio.. Read More»
  DOI: 10.4172/2155-9821.1000153

  Abstract PDF