Journal of Bioengineering & Biomedical Science

James F Antaki

Publications

• Research Article
  Elevated Pressure Aqueous Hemostasis: Experimental and Mathematical Modeling
  Author(s): Matt T Oberdier and James F AntakiMatt T Oberdier and James F Antaki
  
  Elevated Pressure Aqueous Hemostasis is defined as the use of hydrostatic pressure via an isotonic liquid medium in a closed surgical field to control bleeding. It is an effective yet under-characterized means of achieving hemostasis; however, compromised perfusion is a potential complication. Therefore, the objective of this study was to determine the optimal range of extravascular pressure that both limits hemorrhage and allows antegrade flow. A steady-state experimental flow system was employed to simulate series arterial and venous hemodynamics, venous collapse, and arterial hemorrhage. A corresponding lumped-parameter mathematical model, calibrated to experimental data, was then used to extrapolate to conditions of hypotension, normotension, hypertension, limited venous collapse, venous hemorrhage, and simultaneous arterial and venous hemorrhages. Experiments with an elastomeric .. Read More»
  DOI: 10.4172/2155-9538.1000126

  Abstract PDF