Journal of Tissue Science and Engineering

Jan H Spaas

Publications

• Research Article
  Desmitis of the Accessory Ligament of the Equine Deep Digital Flexor Tendon: A Regenerative Approach
  Author(s): Charlotte Beerts, Charlotte Seifert, Marieke Zimmerman, Eduardo Felix, Marc Suls, Tom Mariën, Sarah Broeckx and Jan H SpaasCharlotte Beerts, Charlotte Seifert, Marieke Zimmerman, Eduardo Felix, Marc Suls, Tom Mariën, Sarah Broeckx and Jan H Spaas
  
  Background: Desmitis of the accessory ligament of the deep digital flexor tendon (ALDDFT) is a very common problem in different breeds of sport horses, with an inability to heal adequately after conservative therapy in many cases. However, the treatment of different kinds of tendon lesions with platelet-rich plasma (PRP), mesenchymal stem cells (MSCs), or even tenogenic induced MSCs have been reported with promising results. Methods: After MSC and PRP isolation of the peripheral blood (PB) of a donor horse, tenogenic induction of the MSCs (Tendo-Cell®) was confirmed, and samples were microbiologically tested and frozen. Adverse and clinical effects (macroscopic noticeable swelling, lameness and ultrasound imaging) of PRP (n=4), or Tendo-Cell® (n=4) were evaluated after a single intralesional injection in the ALDDFT in 8.. Read More»
  DOI: 10.4172/2157-7552.1000125

  Abstract PDF