Pulmonary & Respiratory Medicine

Janssens Heleen

Publications

• Research Article
  Analysis of Short and Long Term Variability of Nasal Mucus versus Breath Condensate Inflammation Markers in Healthy Individuals
  Author(s): Janssens Heleen, De Prins Sofie, Schoeters Greet and Koppen GudrunJanssens Heleen, De Prins Sofie, Schoeters Greet and Koppen Gudrun
  
  Objective: Inflammation markers were measured in nasal mucus and exhaled breath condensate (EBC) to assess the normal variability of these markers among healthy individuals. The measurement of protein markers in those matrices is valuable to provide information on inflammation endotypes and local reaction of the immune system. Methods: Inflammation markers (IFN-γ, IL-1β, IL-8, IL-10, IL-13 and TNF-α) in nasal mucus and EBC from six healthy adults were measured by Meso Scale Discovery technology. Nasal mucus was collected with sponges of polyurethane foam, which is a recently developed sampling technique. EBC was sampled via an optimized breath manoeuver with the RTUBETM device. Both collections were done within a limited sampling time of two minutes. The samples were taken on the same day and within a time period of twenty days for the deter.. Read More»
  DOI: 10.4172/2161-105X.1000265

  Abstract PDF