Tehran
West Indies
Research Article
Comparative Histopathological Diagnosis of Cutaneous Melanoma
by H&E, Special Staining and Immunohistochemical Methods against
Cutaneous Squamous Cell Carcinoma in Horse and Bovine
Author(s): Javad Javanbakht, Farhang Sasani, Farajollaheh Adibhashemi and Soheila HemmatiJavad Javanbakht, Farhang Sasani, Farajollaheh Adibhashemi and Soheila Hemmati
Background: The aim of this study was to compare the role of special staining and to test melanoma associated antigens against paraffin embedded bovine and equine melanomas in order to assess their ability and utility as diagnostic tools for diagnosis and confirmation of the melanomas.
Methods: From 1991-2012, 13 cases were reviewed histologically, and each case was found to contain a large focus of melanoma and squamous cell carcinoma (SCC) on the hematoxylin and eosin–stained tissue section. All cases had documented cutaneous melanoma and SCC. Serial 5 μm-thick sections were cut from routine formalinfixed paraffin blocks of 4 case cutaneous SCC (including 2 cases from horses and 2 cases from cattle) and 9 case cutaneous melanomas (including 6 horses cases and 3 cattle cases) from the files of the Department of Pathology have been .. Read More»
DOI:
10.4172/1948-593X.1000103
Journal of Bioanalysis & Biomedicine received 3099 citations as per Google Scholar report