Murcia
Spain
Research Article
Biomarkers of Oxidative Stress in Syndrome Metabolic Patients, a Case Control Study
Author(s): Francisco Avilés-Plaza, Juana Bernabé, Begoña Cerdá, Javier Marhuenda, Pilar Zafrilla, Tânia O. Constantino, Juana Mulero, Cristina García-Viguera, Diego A. Moreno, José Abellán and Soledad Parra-PallarésFrancisco Avilés-Plaza, Juana Bernabé, Begoña Cerdá, Javier Marhuenda, Pilar Zafrilla, Tânia O. Constantino, Juana Mulero, Cristina García-Viguera, Diego A. Moreno, José Abellán and Soledad Parra-Pallarés
Background: Owing to the proposal of the increase of oxidative stress (OxS) as an early event in the development of the metabolic syndrome (MetS), the aim of the present study was to evaluate certain OxS biomarkers in patients with MetS compared to healthy people age-matched and younger to assess the relevance of aging in OxS and MetS.
Methods: A total of 72 patients, 32 who fulfilled the Adult Treatment Panel III criteria for the MetS and 40 individuals without MetS, 20 age-matched to the MetS patients (Control I) and 20 younger subjects (Control II) were studied. We measured several anthropometric and serum parameters and two kinds of molecules related to OxS: modified molecules by reactive oxygen species (ROS) such as oxidized LDL (oxLDLc), and consumed or inducted molecules (enzymes or antioxidants such as Glutathione reductase GR,) asso.. Read More»
DOI:
10.4172/2167-0943.1000187
Journal of Metabolic Syndrome received 48 citations as per Google Scholar report