South Africa
Research Article
Nodal Donovanosis as the Sentinel Clue to Acquired Immunodeficiency Syndrome
Author(s): Pratistadevi K Ramdial, Yetish Sing, Amsha Ramburan, Jayanthilall S Bagratee, Tesuven K Naidu and Bhugwan SinghPratistadevi K Ramdial, Yetish Sing, Amsha Ramburan, Jayanthilall S Bagratee, Tesuven K Naidu and Bhugwan Singh
Abstract Objective: Donovanosis, caused by Calymmatobacterium granulomatis, is a recognized cause of genital ulcer disease. Extragenital donovanosis in acquired immunodeficiency syndrome (AIDS) and lymph nodes is documented rarely. The aim of this report is to highlight implications of lymph node involvement as the initial manifestation of donovanosis, especially in AIDS. Materials and methods: This is a retrospective clinicopathological 6 year study that reviewed the features of lymph node biopsies and patients presenting with nodal donovanosis. Results: Of a total of 198 patients with donovanosis, 4 patients with nodal disease were identified. Patient 1, on anti-tuberculous therapy for pulmonary tuberculosis for 2 weeks, developed subcutaneous nodules on her legs and left-sided inguinal lymphadenopathy. Biopsies confirmed erythema induratum and nodal donovanosis in the former and la.. Read More»
DOI:
10.4172/2155-6113.1000614
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report