Journal of Cytology & Histology

Jean-Louis Boulay

Publications

• Research Article
  Combined Expression of Nestin and SPARC Identifies In Situ Tumor Cells in Astrocytic Tumors of all Grades
  Author(s): Kifah Aljammal, Marie-Françoise Ritz, Archana Ramadoss, Guido Sauter, Jean-Louis Boulay and Luigi MarianiKifah Aljammal, Marie-Françoise Ritz, Archana Ramadoss, Guido Sauter, Jean-Louis Boulay and Luigi Mariani
  
  Background: Malignant gliomas are heterogeneous, diffuse and invasive by nature. Histopathological identification of glioma tumor cells is mandatory to characterize the tumors and the extent of infiltration in the surrounding normal parenchyma. Methods: In order to identify specific markers for tumor cells not expressed in non-neoplastic brain tissues, we used a well-annotated tissue microarray (TMA) containing 45 samples from patients that suffered from several subtypes of low grade and high grade gliomas (pilocytic astrocytoma, oligoastrocytoma, low grade astrocytoma, anaplastic astrocytoma, primary and secondary glioblastomas), non-glial tumors (medulloblastoma and metastasis) as well as fetal, epileptic, and gliotic specimens used as non-tumoral control tissues. The TMA was assessed for 24 proteins involved in tumor proliferation, migratio.. Read More»
  DOI: 10.4172/2157-7099.1000313

  Abstract PDF