Spain
Case Report
Anti-myelin Oligodendrocyte Glycoprotein Autoantibodies in Optic Neuritis and Venous Sinus Thrombosis in a Girl
Author(s): Victor Soto-Insuga, Thais Armangue Salvador, Laura Cabrejas Martinez, Rebeca Losada del Pozo, Maria Rodrigo Moreno, Cristina Ordonez Gonzalez and Jesus Rodriguez CatalanVictor Soto-Insuga, Thais Armangue Salvador, Laura Cabrejas Martinez, Rebeca Losada del Pozo, Maria Rodrigo Moreno, Cristina Ordonez Gonzalez and Jesus Rodriguez Catalan
The anti-myelin oligodendrocyte glycoprotein autoantibody (anti-MOG) is recognized as a new diagnostic and prognostic markers in paediatric acquired demyelinating diseases of the central nervous system. We report a 6 years gril who developed a venous sinus thrombosis and signs of intracranial hypertension after acute otitis media. One month after this infection the patient had an episode of unilateral optic neuritis associated with anti-MOG in serum. Our patient received intravenous steroid treatment and showed a highly favourable response. This is the first case report of demyelinating disease with anti-MOG antibodies associated with thrombophilia.
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DOI:
10.4172/2472-100x.1000109
Journal of Pediatric Neurology and Medicine received 68 citations as per Google Scholar report