St. Jude Children’s Research Hospital,
262 Danny Thomas Place, Memphis, TN 38105
Tanzania
Research Article
Group Sequential Survival Trial Designs Against Historical Controls under the Weibull Model
Author(s): Jianrong Wu and Xiaoping XiongJianrong Wu and Xiaoping Xiong
In this paper, two parametric sequential tests are proposed for historical control trial designs under the Weibull model. The proposed tests are asymptotically normal with properties of Brownian motion. The sample size formulas and information times are derived for both tests. A multi-stage sequential procedure based on sequential conditional probability ratio test methodology is proposed for monitoring clinical trials against historical controls... Read More»
DOI:
10.4172/2155-6180.1000209
Journal of Biometrics & Biostatistics received 3496 citations as per Google Scholar report