Pharmacy Department, College of Medicine and Health Sciences,
Pobox 19, Ambo
Ethiopia
Research Article
Mortality of Adults on Antiretroviral Therapy with and without TB coinfection
in Jimma University Hospital, Ethiopia: Retrospective Cohort Study
Author(s): Jimma Likisa Lenjisa, Sultan Suleman Wega, Tefera Belachew Lema and Gemeda Abebe AyanaJimma Likisa Lenjisa, Sultan Suleman Wega, Tefera Belachew Lema and Gemeda Abebe Ayana
Background: In this study, it was hypothesized that tuberculosis co-infection independently increases the risk of mortality in people living with HIV (PLWHs) even if they are on antiretroviral therapy (ART). Therefore, investigating this hypothesis among cohort of adult PLWHs in south west Ethiopia was the aim of the present work.
Methods: A cohort study was conducted from December to August 2012 at Jimma University Specialized Hospital (JUSH). PLWHs initiating ART between 2008 and 2011 were included using simple random sampling. The effect of TB co-infection on all-cause mortality was assessed using Cox proportional hazard model.
Results: In crude analysis, all-cause mortality of TB co-infected patients was higher by 6.5% (P=0.004). However, multivariate analysis showed that TB co-infection didn’t increase mortality (AHR, 1.31(0.573-3.007), P=0.52). Instead, fac.. Read More»
DOI:
10.4172/2155-6113.1000350
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report