Molecular Biomarkers & Diagnosis

Jiuxiang Lin

Publications

• Review Article
  Salivary Peptidomic Analysis -The Extension of Proteomics
  Author(s): Jieni Zhang, Xueji Zhang, Qingwei Ma, Jiuxiang Lin and Feng ChenJieni Zhang, Xueji Zhang, Qingwei Ma, Jiuxiang Lin and Feng Chen
  
  Nowadays, proteomic-related studies have developed rapidly and improvement has been made in the scientific and technological fields. Besides the proteome, the peptidome with low molecular weight has apparently attracted increasing attention in recent years too. The peptidome performs a large array of vital biological functions to contribute to homeostasis in the certain tissues. However, due to the interference by high-abundance proteins in complex biological body fluids such as saliva and serum, selective enrichment of peptides with low molecular weight is the first and most important step before analyzing the peptidome. This review mainly illustrates the general concept of the peptidome, specific methods of saliva collection, advanced peptidomic technologies and the recently developed peptidomic-related reports, as well as some limitations of the application in salivary peptidome. T.. Read More»
  DOI: 10.4172/2155-9929.1000142

  Abstract PDF